Rate of Adaptation of Large Populations
Rate of Adaptation of Large Populations
复制标题
大量人口的适应率
DOI：
10.1007/978-3-540-78993-2_1
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发表时间：
2008
影响因子：
2.1
通讯作者：
A. Etheridge
中科院分区：
文献类型：
--
作者：
F. Yu;A. Etheridge
我们考虑无性种群中有益和有害突变的积累。适应率受总突变率、有益突变比例和种群规模 N 的影响。我们描述了两种模型：针对较大种群规模的强选择模型和针对中等种群规模的弱选择模型。对于强选择模型，我们给出一个论据来表明，无论突变率如何，只要有益突变的比例严格为正，如果种群规模足够大，适应率至少为 O(log 1−δ N)。对于弱选择模型，我们使用吉尔萨诺夫变换来执行一些初步计算，为适应率提供了新的线索。
We consider the accumulation of beneficial and deleterious mutations in asexual populations. The rate of adaptation is affected by the total mutation rate, proportion of beneficial mutations, and population size N. We describe two models: a strong selection model for large population size and a weak selection model for moderate population size. For the strong selection model, we give an argument to show that regardless of mutation rates, as long as the proportion of beneficial muta- tions is strictly positive, the adaptation rate is at least O(log 1−δ N), if the population size is sufficiently large. For the weak selection model, we use a Girsanov transform to perform some preliminary calculations that shed new light on the adaptation rate.
影响因子：
1.4
作者：
Rouzine, Igor M.;Brunet, Eric;Wilke, Claus O.
通讯作者：
Wilke, Claus O.