A Sterile 20 Family Kinase and Its Co-factor CCM-3 Regulate Contractile Ring Proteins on Germline Intercellular Bridges.

A Sterile 20 Family Kinase and Its Co-factor CCM-3 Regulate Contractile Ring Proteins on Germline Intercellular Bridges.
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DOI:
10.1016/j.cub.2017.01.058
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发表时间:
2017-03-20
期刊:
Current biology : CB
影响因子:
--
通讯作者:
Maddox AS
Maddox AS
中科院分区:
其他
文献类型:
--
作者:
Rehain-Bell K;Love A;Werner ME;MacLeod I;Yates JR 3rd;Maddox AS

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eTOC Blurb Intercellular bridges are proposed to arise from stabilization of a mitotic cytokinetic ring. Rehain-Bell et al. demonstrate that inhibition of non-muscle myosin II is a conserved mechanism of bridge stabilization and find that, in the C. elegans oogenic germline, this is mediated by GCK-1Ste-20 Kinase, its co-factor CCM-3, and anillin proteins.