Development of an atraumatic small centrifugal pump for second-generation cardiopulmonary bypass.
Development of an atraumatic small centrifugal pump for second-generation cardiopulmonary bypass.
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开发用于第二代体外循环的无创伤小型离心泵。
DOI：
10.1111/j.1525-1594.1992.tb00558.x
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发表时间：
2008
影响因子：
2.4
通讯作者：
T. Noda
中科院分区：
文献类型：
--
作者：
T. Jikuya;T. Sasaki;T. Aizawa;M. Shiono;J. Glueck;C. P. Smith;L. Feldman;I. Sakuma;M. Sekela;T. Noda
本文介绍了一种用于体外循环的小型、轻型直驱离心泵。在开发过程中，进行了血液相容性研究，包括溶血研究、体外流体动力学性能研究以及体内耐久性和可行性研究。具有50 mm直径叶轮的离心泵产生与Bio-Medicus离心泵几乎相同的溶血值指数。通过使用柔性驱动电缆防止电机散热。通过使用氟橡胶V形环连接到硬镀铬不锈钢，实现了驱动轴周围48小时的密封耐久性。该泵的体内外性能良好。通过使用有孔叶轮，防止叶轮后面血栓形成，该叶轮产生从叶轮背面到叶轮表面的血流。通过这种改进，在预充过程中消除空气也更容易。该离心泵的起动容量、尺寸和重量是磁耦合离心泵系统的四分之一。
A small and light direct-drive centrifugal pump has been developed for cardiopulmonary bypass. In the development process, blood compatibility studies including a hemolysis study, an in vitro fluid dynamic performance study, and in vivo durability and feasibility studies were performed. The centrifugal pump with a 50 mm diameter impeller resulted in almost the same index of hemolysis value as did a Bio-Medicus centrifugal pump. Heat dissipation from the motor was prevented by using a flexible drive cable. Forty-eight-hour sealing durability around the driving axis was accomplished by using a fluoro-rubber V-ring that connected to the hard chrome-plated stainless steel. In vitro and in vivo performances of the pump were satisfactory. Thrombus formation behind the impeller was prevented by using a holed impeller that generated blood flow from the back to the surface of the impeller. Elimination of air during priming procedures was also easier with this modification. This centrifugal pump has one-quarter of the priming volume, size, and weight of magnetically coupled centrifugal pump systems.