The significance of involvement of a free serosal surface for recurrence and survival following resection of clinicopathological stage B and C rectal cancer

The significance of involvement of a free serosal surface for recurrence and survival following resection of clinicopathological stage B and C rectal cancer
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DOI:
10.1111/j.1463-1318.2006.01136.x
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发表时间:
2007-09-07
期刊:
影响因子:
3.4
通讯作者:
Dent, O. F.
Dent, O. F.
中科院分区:
医学3区
文献类型:
--
作者:
Keshava, A.;Chapuis, P. H.;Dent, O. F.

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目的确定临床病理学B期或C期直肠癌切除且未接受辅助治疗的患者中,游离浆膜面肿瘤的存在是否与盆腔复发或生存独立相关。从1971年1月至1998年12月,随访至2003年12月,所有直肠癌切除术的前瞻性医院登记。统计分析采用卡方检验或Fisher精确概率、Kaplan-Meier估计和比例风险回归,显著性水平为
Objective To determine whether the presence of tumour at a free serosal surface was independently associated with pelvic recurrence or survival in patients who had a resection for clinicopathological stage B or stage C rectal cancer and who had not received adjuvant therapy.Method Data were drawn from a comprehensive, prospective hospital registry of all resections for rectal cancer from January 1971 to December 1998 with follow up to December 2003. Statistical analysis employed the chi(2) test or Fisher's exact probability, Kaplan-Meier estimation and proportional hazards regression, with a significance level of