Standard curves of placental weight and fetal/placental weight ratio in Japanese population: difference according to the delivery mode, fetal sex, or maternal parity
Standard curves of placental weight and fetal/placental weight ratio in Japanese population: difference according to the delivery mode, fetal sex, or maternal parity
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DOI：
10.1016/j.ejogrb.2016.09.004
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发表时间：
2016-11-01
影响因子：
2.6
通讯作者：
Matsubara, Shigeki
中科院分区：
文献类型：
--
作者：
Ogawa, Masaki;Matsuda, Yoshio;Matsubara, Shigeki
目的：胎盘重量（PW）和胎儿/胎盘重量比（F/P）被认为是了解胎儿生长病理生理学的有用参数。然而，在亚洲人群中没有关于PW和F/P的标准数据。本研究旨在建立日本人群的PW和F/P列线图，并阐明该人群的PW和F/P特征。研究设计：本研究包括79，590例日本病例：58，871例阴道分娩和20，719例剖宫产分娩（2001-2002年），并在日本妇产科学会数据库中登记。排除多胎妊娠、死产和胎儿畸形。通过样条方法，按胎儿性别（男性或女性）和母体产次（经产妇或经产妇）分类，创建PW和F/P列线图。结果如下：建立了PW和F/P标准曲线，表明剖宫产时PW和F/P低于阴道分娩，尤其是早产。PW根据胎儿性别和母体产次而不同。结论：本研究首次建立了日本人群的PW和F/P标准曲线，数据统计学上充分，表明剖宫产时PW和F/P均较低。PW和F/P也受胎儿性别的影响。这些数据可能有助于了解子宫内胎儿和胎盘之间的病理生理学。(C)2016爱思唯尔爱尔兰有限公司版权所有。
Objectives: Placental weight (PW) and fetal/placental weight ratio (F/P) have been considered to be useful parameters for understanding the pathophysiology of fetal growth. However, there have been no standard data on PW and F/P in Asian populations. This study was conducted to establish nomograms of PW and F/P in the Japanese population and to clarify characteristics of PW and F/P in this population.Study design: Included in the study were 79,590 Japanese cases: 58,871 vaginal and 20,719 cesarean deliveries at obstetrical facilities (2001-2002) and registered to the Japan Society of Obstetrics and Gynecology Database. Multiple pregnancies, stillbirths, and fetal anomalies were excluded. Nomograms of PW and F/P were created by spline methods in groups categorized by fetal sex (male or female) and maternal parity (primipara or multipara). Results: Standard curves of PW and F/P were established, which indicated that PW and F/P were lower in cesarean deliveries than vaginal deliveries, especially during preterm period. PW differed depending on fetal sex and maternal parity. F/P differed according to fetal sex.Conclusion: We for the first time established standard curves of PW and F/P in the Japanese population with statistically sufficient data, which showed that PW and F/P were lower in cesarean deliveries. PW and F/P were also affected by fetal sex. These data might be useful to understand the pathophysiology between the fetus and placenta in utero. (C) 2016 Elsevier Ireland Ltd. All rights reserved.