Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines.
Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines.
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DOI：
10.3389/fneur.2021.765454
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发表时间：
2021
影响因子：
3.4
通讯作者：
Kivipelto M
中科院分区：
文献类型：
--
作者：
Anstey KJ;Zheng L;Peters R;Kootar S;Barbera M;Stephen R;Dua T;Chowdhary N;Solomon A;Kivipelto M
预防痴呆症是一项全球卫生优先事项。2019年，世界卫生组织发布了首份以证据为基础的减少痴呆症风险指南。我们现在所处的阶段需要有效的工具和资源来评估痴呆症风险，并将这些指导方针落实到政策和实践中。在本文中，我们回顾痴呆风险评分作为一种手段，以促进这一过程。具体来说，我们(a)讨论痴呆症风险评估的基本原理，(b)概述审查风险评分时需要考虑的一些概念和方法问题，(c)评估目前使用的一些痴呆症风险评分，以及(d)对未来方向提出一些评论。痴呆症风险评分是反映个体患痴呆症可能性的风险因素的加权组合。总的来说，痴呆风险评分有广泛的实施和好处，包括提供高风险个体的早期识别，提高患者和医生的风险认知，并帮助卫生专业人员推荐有针对性的干预措施，以改善生活习惯，降低痴呆风险。许多痴呆风险评分已经发表，其中一些被广泛用于研究和临床试验，如CAIDE、ANU-ADRI和LIBRA。然而，使用这些风险评分存在一些方法上的问题和局限性，需要更多的研究来提高它们的有效性和适用性。总的来说，我们得出的结论是，虽然风险评分的进一步完善正在进行中，但有足够的证据表明可以使用这些评估来实施降低痴呆风险的指南。
Dementia prevention is a global health priority. In 2019, the World Health Organisation published its first evidence-based guidelines on dementia risk reduction. We are now at the stage where we need effective tools and resources to assess dementia risk and implement these guidelines into policy and practice. In this paper we review dementia risk scores as a means to facilitate this process. Specifically, we (a) discuss the rationale for dementia risk assessment, (b) outline some conceptual and methodological issues to consider when reviewing risk scores, (c) evaluate some dementia risk scores that are currently in use, and (d) provide some comments about future directions. A dementia risk score is a weighted composite of risk factors that reflects the likelihood of an individual developing dementia. In general, dementia risks scores have a wide range of implementations and benefits including providing early identification of individuals at high risk, improving risk perception for patients and physicians, and helping health professionals recommend targeted interventions to improve lifestyle habits to decrease dementia risk. A number of risk scores for dementia have been published, and some are widely used in research and clinical trials e.g., CAIDE, ANU-ADRI, and LIBRA. However, there are some methodological concerns and limitations associated with the use of these risk scores and more research is needed to increase their effectiveness and applicability. Overall, we conclude that, while further refinement of risk scores is underway, there is adequate evidence to use these assessments to implement guidelines on dementia risk reduction.
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预测2型糖尿病患者10年痴呆风险的风险评分：一项队列研究。
影响因子：
44.5
作者：
Exalto, Lieza G.;Biessels, Geert Jan;Karter, Andrew J.;Huang, Elbert S.;Katon, Wayne J.;Minkoff, Jerome R.;Whitmer, Rachel A.
通讯作者：
Whitmer, Rachel A.
DOI：
10.1590/1980-57642018dn12-030003
发表时间：
2018-07
期刊：
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影响因子：
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影响因子：
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作者：
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影响因子：
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作者：
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通讯作者：
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