Caregiver Burden in Patients Receiving Ranibizumab Therapy for Neovascular Age Related Macular Degeneration.
Caregiver Burden in Patients Receiving Ranibizumab Therapy for Neovascular Age Related Macular Degeneration.
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DOI：
10.1371/journal.pone.0129361
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Sivaprasad S
中科院分区：
文献类型：
--
作者：
Gohil R;Crosby-Nwaobi R;Forbes A;Burton B;Hykin P;Sivaprasad S
评估接受雷珠单抗治疗新生血管性AMD（nAMD）患者的护理负担和决定负担的因素。这是一项横断面问卷调查，在英国三个大型眼科治疗中心对250名匹配的患者护理者进行调查。主要结局是使用照顾者反应评估量表（CRA）测量的主观照顾者负担。客观照顾者负担由照顾者的任务和提供的护理水平决定。还收集了可能预测护理人员负担的因素，如患者较好眼睛的视力和视力相关的生活质量、人口统计学、医疗保健提供的满意度和支持以及二人组的健康状况，并在分层回归模型中进行评估。平均CRA评分为3.2±0.5，与房颤护理人员报告的评分相似，这些护理人员需要定期到医院预约以监测其血栓预防。照顾者的任务，包括陪同医院预约眼科治疗和病人的视力在更好的眼睛是最大的贡献者照顾者负担层次模型解释18%和11%的方差分别。雷珠单抗治疗nAMD与显著的护理者负担相关。疾病影响和治疗频率均对总体负担有贡献。
To assess the caregiver burden and factors determining the burden in patients receiving ranibizumab therapy for neovascular AMD (nAMD). This is a cross-sectional questionnaire survey of 250 matched patient caregiver dyads across three large ophthalmic treatment centres in United Kingdom. The primary outcome was the subjective caregiver burden measured using caregiver reaction assessment scale (CRA). Objective caregiver burden was determined by the caregiver tasks and level of care provided. The factors that may predict the caregiver burden such as the patient’s visual acuity of the better eye and vision related quality of life, demographics, satisfaction and support provided by the healthcare and the health status of the dyads were also collected and assessed in a hierarchical regression model. The mean CRA score was 3.2±0.5, similar to the score reported by caregivers for atrial fibrillation who require regular hospital appointments for monitoring their thromboprophylaxis. Caregiver tasks including accompanying for hospital appointments for eye treatment and patient’s visual acuity in the better eye were the biggest contributors to the caregiver burden hierarchical model explaining 18% and 11% of the variance respectively. Ranibizumab therapy for nAMD is associated with significant caregiver burden. Both disease impact and treatment frequency contributed to the overall burden.
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影响因子：
3.3
作者：
Brooks, R
通讯作者：
Brooks, R
影响因子：
2
作者：
GIVEN, CW;GIVEN, B;FRANKLIN, S
通讯作者：
FRANKLIN, S
影响因子：
5.4
作者：
Nijboer, C;Triemstra, M;van den Bos, GAM
通讯作者：
van den Bos, GAM
影响因子：
3.1
作者：
Hanly, Paul;Maguire, Rebecca;Sharp, Linda
通讯作者：
Sharp, Linda
影响因子：
13.7
作者：
Klein, Ronald;Klein, Barbara E. K.;Gangnon, Ronald E.
通讯作者：
Gangnon, Ronald E.