Economic Burden from Health Losses Due to Foodborne Illness in the United States
Economic Burden from Health Losses Due to Foodborne Illness in the United States
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DOI：
10.4315/0362-028x.jfp-11-058
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发表时间：
2012-01-01
影响因子：
2
通讯作者：
Scharff, Robert L.
中科院分区：
文献类型：
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作者：
Scharff, Robert L.
疾病控制和预防中心（CDC）最近修订了他们对食源性疾病年度数量的估计; 4800万美国人患有与31种已确定病原体和广泛类别的未指明病原体相关的国内获得性食源性疾病。因此，基于先前估计的经济研究现已过时。这项研究的目的是通过在现有的疾病成本模型中增加2011年CDC模型的复制，提供对食源性疾病成本的改进和更新估计。基本的疾病成本模型包括对医疗成本、生产力损失和疾病相关死亡率的经济估计（基于生命享乐价值研究）。增强的疾病成本模型取代了生产力损失的估计，更包容的疼痛，痛苦和功能残疾的措施，根据货币化的质量调整生命年估计。对每种病原体和更广泛类别的未知病原体的成本进行了估计。增加最新的成本数据和改进方法提高了每个现有经济模型的性能。这些模型的不确定性使用@Risk 5.5版中的Monte Carlo模拟进行表征。使用该模型，增强型疾病成本模型的每例食源性疾病的平均成本为1，626美元（90%可信区间[CI]为607至3，073美元），基本模型为1，068美元（90% CI为683至1，646美元）。由此产生的疾病年度总成本为777亿美元（90% CI）。286亿至1446亿美元）和510亿美元（90% CI。312亿美元至761亿美元）。
The Centers for Disease Control and Prevention (CDC) recently revised their estimates for the annual number of foodborne illnesses; 48 million Americans suffer from domestically acquired foodborne illness associated with 31 identified pathogens and a broad category of unspecified agents. Consequently, economic studies based on the previous estimates are now obsolete. This study was conducted to provide improved and updated estimates of the cost of foodbome illness by adding a replication of the 2011 CDC model to existing cost-of-illness models. The basic cost-of-illness model includes economic estimates for medical costs, productivity losses, and illness-related mortality (based on hedonic value-of-statistical-life studies). The enhanced cost-of-illness model replaces the productivity loss estimates with a more inclusive pain, suffering, and functional disability measure based on monetized quality-adjusted life year estimates. Costs are estimated for each pathogen and a broader class of unknown pathogens. The addition of updated cost data and improvements to methodology enhanced the performance of each existing economic model. Uncertainty in these models was characterized using Monte Carlo simulations in @Risk version 5.5. With this model, the average cost per case of foodborne illness was $1,626 (90% credible interval [CI] $607 to $3,073) for the enhanced cost-of-illness model and $1,068 (90% CI, $683 to $1,646) for the basic model. The resulting aggregated annual cost of illness was $77.7 billion (90% CI. $28.6 to $144.6 billion) and $51.0 billion (90% CI. $31.2 to $76.1 billion) for the enhanced and basic models, respectively.