Neuropsychological functioning in adults with Asperger syndrome
Neuropsychological functioning in adults with Asperger syndrome
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DOI：
10.1177/1362361306068507
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发表时间：
2006-11-01
期刊：
影响因子：
5.2
通讯作者：
Murphy, Declan G. M.
中科院分区：
文献类型：
--
作者：
Ambery, Fiona Z.;Russell, Ailsa J.;Murphy, Declan G. M.
关于阿斯伯格综合症（AS）患者的认知特征，文献中存在一些共识。迄今为止的研究结果表明，一部分 AS 患者的语言智商高于表现智商，存在非语言学习障碍 (NVLD) 以及执行功能 (EF) 某些方面的障碍。然而，关于成人 AS 的已发表研究很少，而且许多研究仅将 AS 组与自闭症对照组进行比较。我们比较了 27 名没有语言发育迟缓史的 AS 成年人和 20 名在年龄、性别和智商上没有显着差异的正常对照者的认知功能。患有 AS 的人在视觉记忆测试和测量灵活性和生成性的 EF 任务中存在显着障碍，但在抑制力方面没有显着障碍。言语智商和表现智商之间没有显着差异。我们的结果表明，在需要思维和生成灵活性的测试中，所有年龄段以及包括 AS 在内的一系列自闭症患者都会出现障碍。
There is some consensus in the literature regarding the cognitive profile of people with Asperger syndrome (AS). Findings to date suggest that a proportion of people with AS have higher verbal than performance IQ, a non-verbal learning disability (NVLD) and impairments in some aspects of executive function (EF). However, there are few published studies on adults with AS and many have compared the AS group to an autistic control group alone. We compared cognitive functioning in 27 AS adults without a history of language delay and 20 normal controls who did not differ significantly in age, gender and IQ. People with AS had significant impairments on a test of visual memory and on EF tasks measuring flexibility and generativity, but not inhibition. There was no significant difference between verbal and performance IQ. Our results suggest that impairments on tests requiring flexibility of thought and generation occur at all ages and across a range of autistic disorders including AS.