The effects of individual nonheritable variation on fitness estimation and coexistence
The effects of individual nonheritable variation on fitness estimation and coexistence
复制标题
个体非遗传变异对适应度估计和共存的影响
作者：
M. Gabriela M. Gomes;Jessica G. King;A. Nunes;N. Colegrave;A. Hoffmann
人口统计学理论和数据强调，个体脆弱性的不可遗传变异使群体内的选择成为可能，影响种群的动态，同时对种群的进化是不可见的。在这里，我们包括在简单的细菌生长模型中不可遗传的寿命或生存能力的个体变异的组成部分，并探索其生态和进化的影响。首先，我们发现，这种变化产生一致的趋势，细菌基因型之间的寿命差异时，跨应力梯度测量。鉴于直接测量寿命是不可避免的偏见，由于存在这种变化和正在进行的选择，我们建议使用的趋势本身获得更准确的推断基因型健身。其次，我们展示了物种或菌株共存如何能够通过寿命或生存能力的非遗传变异来实现。这些一般性的结论很可能超出细菌系统。
Abstract Demographic theory and data have emphasized that nonheritable variation in individual frailty enables selection within cohorts, affecting the dynamics of a population while being invisible to its evolution. Here, we include the component of individual variation in longevity or viability which is nonheritable in simple bacterial growth models and explore its ecological and evolutionary impacts. First, we find that this variation produces consistent trends in longevity differences between bacterial genotypes when measured across stress gradients. Given that direct measurements of longevity are inevitably biased due to the presence of this variation and ongoing selection, we propose the use of the trend itself for obtaining more exact inferences of genotypic fitness. Second, we show how species or strain coexistence can be enabled by nonheritable variation in longevity or viability. These general conclusions are likely to extend beyond bacterial systems.