Cholangiolocellular Carcinoma of the Liver: Imaging Findings
Cholangiolocellular Carcinoma of the Liver: Imaging Findings
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DOI：
10.1097/rct.0b013e318195400c
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发表时间：
2009-09-01
影响因子：
1.3
通讯作者：
Yamaguchi, Hiroshi
中科院分区：
文献类型：
--
作者：
Motosugi, Utaroh;Ichikawa, Tomoaki;Yamaguchi, Hiroshi
目的：胆管细胞癌（CLC）是肝内胆管细胞癌的一种罕见亚型，根据世界卫生组织的标准分类。最近的研究还表明，CLC可能来源于肝祖细胞，肝祖细胞是肝脏特异性干细胞。我们回顾了CLC的影像学表现，包括肝内转移瘤的影像学表现。图像，包括动态计算机断层扫描和磁共振images.Results：在动脉期图像，病变表现为肿块表现出早期和完全增强或主要周边增强。在一半病变中观察到造影剂在病变中滞留。转移性结节边界不清，早期增强沿着增强，中心延迟增强。结论：尽管中心致密纤维化的CLC表现出与肝内胆管细胞癌相似的影像学特征，但早期增强伴持续延迟增强是这种罕见肿瘤的特征性影像学表现之一。
Objective: Cholangiolocellular carcinoma (CLC) is a rare subtype of intrahepatic cholangiocarcinoma as categorized according to the World Health Organization criteria. Recent study also revealed that CLC would originate from hepatic progenitor cells, which are liver-specific stem cells. We reviewed the imaging findings of CLCs, including those of intrahepatic metastases.Methods: Eight patients who underwent partial hepatectomy were included in this Study. Images, including dynamic computed tomographic and magnetic resonance images, were reviewed.Results: On arterial phase images, the lesions appeared as masses exhibiting early and complete enhancement or predominantly peripheral enhancement. Retention of the contrast media in the lesions was observed in half of the lesions. The metastatic nodules had indistinct borders and showed early enhancement along with delayed central enhancement.Conclusions: Although CLC with dense central fibrosis exhibits imaging features similar to those exhibited by intrahepatic cholangliocarcinoma, early enhancement in most lesions with persistent delayed enhancement is one of the characteristic imaging findings of this rare tumor.