Multiple 3D Inversion Recovery Imaging for Volume T1 Mapping of the Heart
Multiple 3D Inversion Recovery Imaging for Volume T1 Mapping of the Heart
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DOI：
10.1002/mrm.24248
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发表时间：
2013-01-01
影响因子：
3.3
通讯作者：
Begnozzi, L.
中科院分区：
文献类型：
--
作者：
Coniglio, A.;Di Renzi, P.;Begnozzi, L.
在这篇文章中，三维反转恢复序列进行了优化，目的是在体内体积T1地图的心脏使用1.5 T MR系统。采集前和后钆二亚乙基三胺五乙酸（Gd-DTPA）管理肥厚型心肌病患者和两名健康志愿者。使用ECG和呼吸触发器，通过多次激发快速场回波读数采集数据。将由具有不同T1值的四种溶液组成的专用体模放置在受试者的胸部区域，以执行患者特定校准。基于像素的T1图用自定义Matlabf（R）代码计算。体模测量显示该技术具有良好的准确性，肝脏、骨骼肌、心肌和血液的体内T1估计与文献中报告的值具有良好的一致性。多重三维反演恢复技术是一种可行的、精确的T1容积成像方法。Magn Reson Med，2013年。(c)2012 Wiley Periodicals，Inc.
In this article, a three-dimensional inversion recovery sequence was optimized with the aim of generating in vivo volume T1 maps of the heart using a 1.5-T MR system. Acquisitions were performed before and after gadolinium diethylenetriamine penta-acetic acid (Gd-DTPA) administration in one patient with hypertrophic cardiomyopathy and in two healthy volunteers. Data were acquired with a multishot fast field echo readout using both ECG and respiratory triggers. A dedicated phantom, composed of four solutions with different T1 values, was positioned on the subjects' thoracic region to perform patient-specific calibration. Pixel based T1 maps were calculated with a custom Matlabf (R) code. Phantom measurements showed a good accuracy of the technique and in vivo T1 estimation of liver, skeletal muscle, myocardium, and blood resulted in good agreement with values reported in the literature. Multiple three-dimensional inversion recovery technique is a feasible and accurate method to perform T1 volume mapping. Magn Reson Med, 2013. (c) 2012 Wiley Periodicals, Inc.