Allergenically active components of cat allergen extracts.

Allergenically active components of cat allergen extracts.
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猫过敏原提取物的过敏活性成分。

DOI:
10.4049/jimmunol.127.3.972
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发表时间:
1981
影响因子:
4.4
通讯作者:
H. Baer
H. Baer
中科院分区:
医学2区
文献类型:
--
作者:
M. Anderson;H. Baer

文献摘要

被引文献

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猫过敏的过敏原已经在毛皮提取物、唾液、血清和尿液中进行了研究。用交叉免疫电泳(CIE)检测抗原含量,用交叉放射免疫电泳(CRIE)和RAST检测变应原含量,结果表明:Dr.Ohman的变应原1是最重要的变应原成分,而白蛋白和几种未鉴定的蛋白质起次要作用。血清和尿液中未检测到过敏原1。经CIE分析,毛皮提取物和唾液中的致敏蛋白和非致敏蛋白一致,表明毛皮提取物蛋白主要来源于唾液。
The allergens involved in cat allergy have been studied in pelt extracts, saliva, serum, and urine. Using crossed immunoelectrophoresis (CIE) to examine the antigenic content, and crossed radioimmunoelectrophoresis (CRIE) and RAST to examine the allergenic content, it was found that allergen 1 of Dr. Ohman is the most important allergenic component, whereas albumin and several unidentified proteins play a minor role. Allergen 1 was not detectable in serum and urine. The allergenic and nonallergenic proteins of pelt extract and saliva were identical by CIE, suggesting that pelt extract proteins are mainly of salivary origin.