From circuits to behavior: a bridge too far?

From circuits to behavior: a bridge too far?
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DOI:
10.1038/nn.3043
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发表时间:
2012-04-01
影响因子:
25
通讯作者:
Carandini, Matteo
Carandini, Matteo
中科院分区:
医学1区
文献类型:
--
作者:
Carandini, Matteo

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神经科学试图了解神经回路如何导致行为。然而,电路和行为之间的差距太大了。中间层是神经计算之一,发生在单个神经元和神经元群体中。有些计算似乎是规范的:在大脑中以不同的方式重复和组合。为了理解神经计算,我们必须记录多个大脑区域的无数神经元。理解计算可以指导底层电路的研究,并为行为理论提供一种语言。
Neuroscience seeks to understand how neural circuits lead to behavior. However, the gap between circuits and behavior is too wide. An intermediate level is one of neural computations, which occur in individual neurons and populations of neurons. Some computations seem to be canonical: repeated and combined in different ways across the brain. To understand neural computations, we must record from a myriad of neurons in multiple brain regions. Understanding computation guides research in the underlying circuits and provides a language for theories of behavior.