Magnetic resonance imaging of left atrial thrombus
Magnetic resonance imaging of left atrial thrombus
复制标题
左心房血栓磁共振成像
作者：
Li Wei;J. Wang;P. Thompson;S. Wong;A. Struthers;T. MacDonald
目的：研究首次心肌梗死（MI）后患者对他汀类药物治疗的依从性，并评估依从他汀类药物对MI复发和全因死亡率的影响。设计：队列研究，使用记录链接数据库。地点：Tayside，Scotland，UK患者：1990年1月至1995年11月期间首次发生MI的患者。主要结果指标：MI后患者使用他汀类药物和坚持使用他汀类药物的百分比以及因复发性MI住院的相对风险。还检查了依从性对全因死亡率的影响。使用的协变量为年龄、性别、社会经济贫困、血清胆固醇浓度、糖尿病、心血管药物使用和其他住院情况。结果：在发生MI事件的5590例患者中，717例（12.8%）发生了至少一次进一步的MI。在研究期间，只有7.7%的患者在MI后使用他汀类药物。与未服用他汀类药物的患者相比，对他汀类药物治疗依从性为80%或更好的患者的MI复发校正相对风险为0.19（95%置信区间（CI）0.08至0.47），全因死亡率为0.47（95% CI 0.22至0.99）。对于那些他汀类药物依从性低于80%的患者，两个终点均无显著降低。结论：尽管在研究期间很少使用他汀类药物，但良好的他汀类药物治疗依从性与MI复发风险降低相关。
Objective: To investigate patients' adherence to statin treatment prescribed following their first myocardial infarction (MI) and to estimate the effect of adherence to statins on recurrence of MI and all cause mortality. Design: Cohort study using a record linkage database. Setting: Tayside, Scotland, UK. Patients: Patients who experienced their first MI between January 1990 and November 1995. Main outcome measures: Percentage of statin use and adherence to statins by patients after an MI and the relative risk of hospitalisation for recurrent MI. The effect of adherence on all cause mortality was also examined. The covariates used were age, sex, socioeconomic deprivation, serum cholesterol concentration, diabetes mellitus, cardiovascular drug use, and other hospitalisations. Results: Of 5590 patients who experienced an incident MI, 717 (12.8%) experienced at least one further MI. Only 7.7% of patients used statins after an MI during the study period. Compared with those not taking statins, those who had 80% or better adherence to statin treatment had an adjusted relative risk of recurrent MI of 0.19 (95% confidence interval (CI) 0.08 to 0.47) and all cause mortality of 0.47 (95% CI 0.22 to 0.99). There was no significant reduction in either end point for those who were less than 80% adherent to statins. Conclusions: Despite the infrequent use of statin during the study period, good adherence to statin treatment was associated with lower risk of recurrent MI.
影响因子：
--
作者：
McBride, P;Schrott, HG;Brown, RL
通讯作者：
Brown, RL
影响因子：
37.8
作者：
Maron, DJ;Fazio, S;Linton, MF
通讯作者：
Linton, MF