The impact of probiotics and prebiotics on the immune system
The impact of probiotics and prebiotics on the immune system
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DOI：
10.1038/nri3312
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发表时间：
2012-10-01
影响因子：
100.3
通讯作者：
Rescigno, Maria
中科院分区：
文献类型：
--
作者：
Klaenhammer, Todd R.;Kleerebezem, Michiel;Rescigno, Maria
益生菌和益生元越来越多地被添加到声称对健康有益的食品中。益生菌是被认为对宿主具有有益作用的活微生物，而益生元是刺激有益肠道微生物的生长和/或功能的成分。但这些产品是否可以直接调节免疫功能并影响炎症性疾病？在这里，自然评论免疫学邀请四位专家讨论这些问题，并提供他们对益生菌作为疾病治疗的未来应用的想法。
Probiotics and prebiotics are increasingly being added to foodstuffs with claims of health benefits. Probiotics are live microorganisms that are thought to have beneficial effects on the host, whereas prebiotics are ingredients that stimulate the growth and/or function of beneficial intestinal microorganisms. But can these products directly modulate immune function and influence inflammatory diseases? Here, Nature Reviews Immunology asks four experts to discuss these issues and provide their thoughts on the future application of probiotics as a disease therapy.