Macromolecule crowding effects on the phase separation of semi-flexible polymer in spherical confined space
Macromolecule crowding effects on the phase separation of semi-flexible polymer in spherical confined space
复制标题
球状受限空间内高分子拥挤对半柔性聚合物相分离的影响
DOI：
10.1007/s10867-020-09550-9
复制
发表时间：
2020-06
影响因子：
1.8
通讯作者：
Yanhui Liu
中科院分区：
文献类型：
--
作者：
Hongchang Wang;Lingyun Gu;Rongri Tan;Xiaotian Ma;Xun Zhou;Yanhui Liu
目前的工作集中在检测的大分子拥挤效应之间的半柔性聚合物和crowders（亲水性聚合物）的混合物在受限空间中的相分离的Monte Carlo模拟。随着crowders的加入，半柔性聚合物首先从初始的卷曲态压缩成凝聚态，然后凝聚态以伸展态膨胀并沉积在球形受限空间的内表面。在相空间中用crowder体积分数和crowder直径标度球形受限空间半径的相图以及半柔性聚合物的直接构象转变验证了相变过程。此外，扩展构象在球形受限空间内表面的沉积由顶点密度来表征，其曲线随着crowder体积分数的增加而沿着径向移动。在相分离过程中，临界体积分数φ_c与拥挤直径近似线性相关，临界体积分数与拥挤直径之间的关系强烈依赖于球形受限空间的大小。
Current works focus on detecting macromolecule crowding effects on the phase separation of the mixture between semi-flexible polymer and crowders (hydrophilic polymers) in confined space by Monte Carlo simulations. With the increasing addition of crowders into the spherical confined space, the semi-flexible polymer was first compressed into a condensed state from the initial coil state, and then the condensed conformation expanded and deposited on the inner surface of the spherical confined space with an extended state. The phase diagram in the phase space of the volume fraction of crowders and the scaled radius of spherical confined space by crowder diameter, and the direct conformation transition of semi-flexible polymer have validated the phase transition process successfully. In addition, the deposition of extended conformation on the inner surface of the spherical confined space was qualified by the vertex density, its curve shifted along the radial direction with the increasing volume fraction of crowder. During the phase separation process, the critical volume fractionφ∗relates to the crowder diameter approximately linearly and the relation between the critical volume fraction and the crowder diameter strongly depends on the size of the spherical confined space.
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影响因子：
3.7
作者：
Fujiwara K;Nomura SM
通讯作者：
Nomura SM
影响因子：
3.7
作者：
Ge X;Luo D;Xu J
通讯作者：
Xu J
DOI：
10.1103/physreve.91.050601
发表时间：
2015-03
期刊：
Physical review. E, Statistical, nonlinear, and soft matter physics
影响因子：
--
作者：
E. Werner;Bernhard Mehlig
通讯作者：
E. Werner;Bernhard Mehlig
影响因子：
64.8
作者：
Adams, M;Dogic, Z;Fraden, S
通讯作者：
Fraden, S
影响因子：
64.5
作者：
Delarue, M.;Brittingham, G. P.;Pfeffer, S.;Surovtsev, I. V.;Pinglay, S.;Kennedy, K. J.;Schaffer, M.;Gutierrez, J. I.;Sang, D.;Poterewicz, G.;Chung, J. K.;Plitzko, J. M.;Groves, J. T.;Jacobs-Wagner, C.;Engel, B. D.;Holt, L. J.
通讯作者：
Holt, L. J.