Left ventricular volume calculation using a count-based ratio method applied to first-pass radionuclide angiography.
Left ventricular volume calculation using a count-based ratio method applied to first-pass radionuclide angiography.
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使用应用于首过放射性核素血管造影的基于计数的比率方法计算左心室容积。
DOI：
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发表时间：
1990
影响因子：
9.3
通讯作者：
Steven C. Port
中科院分区：
文献类型：
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作者：
Teresa Massardo;Rami Gal;R. P. Grenier;Donald H. Schmidt;Steven C. Port
用于计算左心室容积的大多数基于计数的放射性核素方法依赖于对外周血样本中的放射性的测量以及对心室到准直器距离的测量。我们已经开发出一种方法，既不需要血液样本，也不需要距离测量，这是适用于首次通过放射性核素血管造影。用于计算体积的参数是像素面积、左心室中的总计数和最大像素计数。该公式用于计算50例患者的体积，这些患者在同一天进行了静息首过放射性核素血管造影（25例患者使用单晶相机，25例患者使用多晶相机）和对比心室造影。舒张末期和收缩末期容积的相关系数显示r范围为0.93-0.98，舒张末期容积的估计标准误差范围为23-35 ml（平均舒张末期容积的14%-17%），收缩末期容积的估计标准误差范围为16-23 ml（平均收缩末期容积的18%-21%）。用于提取所需值的图像处理软件通常可在大多数商业核医学成像系统上获得，并且用于计算的附加时间很短。尽管该理论基于多个假设，但体积计算似乎相当准确且临床适用。
Most count-based radionuclide methods for calculating left ventricular volume rely on measurement of radioactivity in a peripheral blood sample and a measurement of ventricle to collimator distance. We have developed a method which requires neither a blood sample nor a distance measurement and which is applicable to first-pass radionuclide angiography. The parameters used to calculate volume are the area of pixel, the total counts in the left ventricle and the maximum pixel count. The equation was used to calculate the volumes in 50 patients who had both resting first-pass radionuclide angiography (25 patients with a single crystal and 25 patients with a multicrystal camera) and contrast ventriculography on the same day. Correlation coefficients for end-diastolic and end-systolic volumes showed r ranging 0.93-0.98 and standard error of estimate ranging 23-35 ml for end-diastolic volume (14%-17% of mean end-diastolic volume) and 16-23 ml for end-systolic volume (18%-21% of mean end-systolic volume). Image processing software for extracting the needed values is generally available on most commercial nuclear medicine imaging systems and the additional time for the calculations is short. Although the theory is based on multiple assumptions, the volume calculation appears to be reasonably accurate and clinically applicable.