Vicarious responses to pain in anterior cingulate cortex: Is empathy a multisensory issue?
Vicarious responses to pain in anterior cingulate cortex: Is empathy a multisensory issue?
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DOI：
10.3758/cabn.4.2.270
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发表时间：
2004-06-01
影响因子：
2.9
通讯作者：
Roberts, Neil
中科院分区：
文献类型：
--
作者：
Morrison, India;Lloyd, Donna;Roberts, Neil
功能性磁共振成像的结果表明，感觉指尖中度疼痛的针刺刺激和目睹另一个人的手经历类似的刺激与右背前扣带皮层（ACC）疼痛相关区域的共同活动有关。对有害的触觉和视觉刺激作出反应的共同活动仅限于右下布罗德曼区24 b。这些结果表明，在没有明显的象征性线索的情况下，发生在陌生人身上的令人厌恶的生态事件的感觉和看到的疼痛有一个共同的神经基质。与ACC 24 b相反，初级躯体感觉皮层对有害和无害的触觉刺激都表现出显著的激活，但对视觉刺激没有反应。在这两个领域的不同的反应模式是一致的ACC的编码的动机情感维度的疼痛，这是与准备的行为反应厌恶事件的作用。
Results obtained with functional magnetic resonance imaging show that both feeling a moderately painful pinprick stimulus to the fingertips and witnessing another person's hand undergo similar stimulation are associated with common activity in a pain-related area in the right dorsal anterior cingulate cortex (ACC). Common activity in response to noxious tactile and visual stimulation was restricted to the right inferior Brodmann's area 24b. These results suggest a shared neural substrate for felt and seen pain for aversive ecological events happening to strangers and in the absence of overt symbolic cues. In contrast to ACC 24b, the primary somatosensory cortex showed significant activations in response to both noxious and innocuous tactile, but not visual, stimuli. The different response patterns in the two areas are consistent with the ACC's role in coding the motivational-affective dimension of pain, which is associated with the preparation of behavioral responses to aversive events.