Breast cancer in adolescents and young adults.

Breast cancer in adolescents and young adults.
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青少年和年轻人的乳腺癌。

DOI:
10.1002/pbc.27397
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发表时间:
2018-12
影响因子:
3.2
通讯作者:
Bleyer A
Bleyer A
中科院分区:
医学3区
文献类型:
--
作者:
Johnson RH;Anders CK;Litton JK;Ruddy KJ;Bleyer A

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乳腺癌是15至39岁的青少年和年轻成年(AYA)女性最常见的癌症,占女性所有浸润性乳腺癌的5.6%。与老年女性相比,AYA更可能具有家族性癌症易感基因、较大的乳腺肿瘤、不利的生物学特征、诊断时的远处转移性疾病和不良结局。内分泌治疗和一些化疗的建议不同的年轻和老年妇女。AYA需要协调的多学科护理,治疗方案,最大限度地减少后期影响,如过早绝经和骨质疏松症,并积极主动地管理心理和性健康期间和之后的癌症治疗。
Breast cancer is the most common cancer of adolescents and young adult (AYA) women aged 15 to 39 years, accounting for 5.6% of all invasive breast cancer in women. In comparison to older women, AYAs are more likely to have familial cancer predisposition genes, larger breast tumors, unfavorable biological characteristics, distant metastatic disease at diagnosis, and adverse outcome. Endocrine therapy and some chemotherapy recommendations differ between young and older women. AYAs require coordinated multidisciplinary care, treatment regimens that minimize late effects such as premature menopause and osteoporosis, and proactive management of psychological and sexual health during and after cancer treatment.
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影响因子: 11.5
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