Validity and reliability of dual-energy X-ray absorptiometry for the assessment of abdominal adiposity
Validity and reliability of dual-energy X-ray absorptiometry for the assessment of abdominal adiposity
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DOI：
10.1152/japplphysiol.01234.2003
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发表时间：
2004-08-01
影响因子：
3.3
通讯作者：
Dengel, DR
中科院分区：
文献类型：
--
作者：
Glickman, SG;Marn, CS;Dengel, DR
存在许多方法用于估计腹部肥胖，范围从腰臀比到计算机断层扫描（CT）。虽然双能X射线吸收法（DXA）最初用于测量骨密度和全身成分，但最近软件的改进使其能够确定腹部脂肪量。65名年龄在18-72岁的男性和女性参加了一系列研究，以检查DXA准确测量腹部脂肪的有效性和可靠性。使用Lunar DPX-IQ通过DXA测量全身脂肪和腹部区域脂肪。使用Picker PQ 5000 CT扫描仪在L1和L4椎体（感兴趣区域）之间进行多层螺旋CT扫描，并在Voxel Q工作站上进行体积分析。与多层螺旋CT相比，DXA测量的L1-L4感兴趣区域的腹部总组织质量（P = 0.02）和腹部脂肪质量（P < 0.0001）均显著降低。然而，Bland-Altman分析表明，DXA和CT在腹部总组织质量方面具有良好的一致性（即，一致性限度= -1.56-2.54kg）和脂肪量（即，一致性限度= -0.40-1.94 kg）。DXA也显示了良好的可靠性，在三个不同的运营商，以确定总，脂肪，瘦体重在L1-L4的利益（组内相关性，R = 0.94，0.97，和0.89，分别）。总之，DXA L1-L4感兴趣区域与CT相比被证明是确定腹部肥胖的可靠和准确的方法。
A number of methods exist for the estimation of abdominal obesity, ranging from waist-to-hip ratio to computed tomography (CT). Although dual-energy X-ray absorptiometry (DXA) was originally used to measure bone density and total body composition, recent improvements in software allow it to determine abdominal fat mass. Sixty-five men and women aged 18-72 yr participated in a series of studies to examine the validity and reliability of the DXA to accurately measure abdominal fat. Total body fat and abdominal regional fat were measured by DXA using a Lunar DPX-IQ. Multislice CT scans were performed between L1 and L4 vertebral bodies (region of interest) using a Picker PQ5000 CT scanner, and volumetric analyses were carried out on a Voxel Q workstation. Both abdominal total tissue mass (P = 0.02) and abdominal fat mass (P < 0.0001) in the L1-L4 region of interest were significantly lower as measured by DXA compared with multislice CT. However, Bland-Altman analysis demonstrated good concordance between DXA and CT for abdominal total tissue mass (i.e., limits of agreement = -1.56-2.54 kg) and fat mass (i.e., limits of agreement = -0.40-1.94 kg). DXA also showed excellent reliability among three different operators to determine total, fat, and lean body mass in the L1-L4 region of interest (intraclass correlations, R = 0.94, 0.97, and 0.89, respectively). In conclusion, the DXA L1-L4 region of interest compared with CT proved to be both reliable and accurate method to determine abdominal obesity.