Influence of age on size and number of fat cells in the epididymal depot.
Influence of age on size and number of fat cells in the epididymal depot.
复制标题
年龄对附睾库中脂肪细胞大小和数量的影响。
DOI：
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发表时间：
1975
影响因子：
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通讯作者：
E. Masoro
中科院分区：
文献类型：
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作者：
J. Stiles;A. Francendese;E. Masoro
关于老鼠年龄对脂肪组织中脂肪细胞的大小和数量的影响的大量文献仅涉及发育中的幼鼠和青壮年。因此，本实验室对Fisher 344品系大鼠附睾库的细胞特性进行了研究。从9周龄、13周龄、26周龄、52周龄、104周龄和130周龄的大鼠身上制备的胶原酶消化液产生了直径大于30微米的细胞群，被鉴定为脂肪细胞或“脂肪细胞”。在大鼠的一生中，附睾库中这些脂肪细胞的大小和数量都发生了非常复杂的变化。附睾库还含有一些直径约10微米的细胞，其形态与经典的脂肪细胞相似，这些细胞可能是前脂肪细胞。
The extensive literature on the effect of rat age on the size and number of adipocytes in adipose tissue depots relates solely to young developing rats and young adults. Therefore a study was carried out in our laboratory on the cellular characteristics of the epididymal depot of the Fisher 344 strain of rats through virtually the entire life-span. Collagenase digests of this depot prepared from rats of 9, 13, 26, 52, 104, and 130 wk of age yield a population of cells with diameters greater than 30 mum identified as adipocytes or "fat cells." A remarkably complex pattern of changes in both the size and the number of these fat cells in the epididymal depot occurred through the life-span of the rats. The epididymal depots also contain some cells with diameters around 10 mum which have a morphology similar to that of the classic adipocytes; such cells may be preadipocytes.