HETEROGENEITY IN EPIDERMAL BASAL KERATINOCYTES - MORPHOLOGICAL AND FUNCTIONAL CORRELATIONS
HETEROGENEITY IN EPIDERMAL BASAL KERATINOCYTES - MORPHOLOGICAL AND FUNCTIONAL CORRELATIONS
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DOI：
10.1126/science.7058342
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发表时间：
1982-01-01
期刊：
影响因子：
56.9
通讯作者：
SUN, TT
中科院分区：
文献类型：
--
作者：
LAVKER, RM;SUN, TT
在食蟹猴和人手掌表皮中观察到两个结构不同的基底角质形成细胞群，即非锯齿状和锯齿状。解剖位置、精细结构特征和动力学特性表明，非锯齿状细胞代表干细胞群，而锯齿状细胞有助于将表皮锚定到真皮。
Two structurally distinct populations of basal keratinocytes, nonserrated and serrated, were observed in cynomolgus monkey and human palm epidermis. Anatomical location, fine structural features and kinetic properties suggest that nonserrated cells represent a stem cell population and that serrated cells help anchor the epidermis to the dermis.