Downregulation of the Posterior Medial Frontal Cortex Prevents Social Conformity
Downregulation of the Posterior Medial Frontal Cortex Prevents Social Conformity
复制标题
DOI：
10.1523/jneurosci.1869-11.2011
复制
发表时间：
2011-08-17
影响因子：
5.3
通讯作者：
Fernandez, Guillen
中科院分区：
文献类型：
--
作者：
Klucharev, Vasily;Munneke, Moniek A. M.;Fernandez, Guillen
我们经常改变自己的行为以适应真实或想象的群体压力。社会心理学对社会对我们行为的影响进行了广泛的研究，但其神经机制仍然很大程度上未知。在这里，我们证明了θ爆发经颅磁刺激对后内侧额叶皮层的短暂下调会降低从众性，正如与群体意见一致的适形调整减少所表明的那样。相对于假手术和对另一个大脑区域的控制刺激，适形行为调整的程度和概率均显着下降。内侧额叶皮层的后部此前曾与行为和态度的调整有关。在这里，我们提供了第一个干预证据，证明其在社会影响人类行为中的关键作用。
We often change our behavior to conform to real or imagined group pressure. Social influence on our behavior has been extensively studied in social psychology, but its neural mechanisms have remained largely unknown. Here we demonstrate that the transient downregulation of the posterior medial frontal cortex by theta-burst transcranial magnetic stimulation reduces conformity, as indicated by reduced conformal adjustments in line with group opinion. Both the extent and probability of conformal behavioral adjustments decreased significantly relative to a sham and a control stimulation over another brain area. The posterior part of the medial frontal cortex has previously been implicated in behavioral and attitudinal adjustments. Here, we provide the first interventional evidence of its critical role in social influence on human behavior.