Minimal Erythema Dose (MED) Testing
Minimal Erythema Dose (MED) Testing
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DOI：
10.3791/50175
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发表时间：
2013-05-01
影响因子：
1.2
通讯作者：
Oslin, David W.
中科院分区：
文献类型：
--
作者：
Heckman, Carolyn J.;Chandler, Rachel;Oslin, David W.
紫外线治疗有时被用来治疗各种常见的皮肤病，包括牛皮癣、粉刺和湿疹。紫外线的剂量是根据个人的皮肤敏感度而定的。因此，为了确定对患者进行紫外线照射的适当剂量，有时会对患者进行筛查，以确定最小红斑剂量(MED)，这是在暴露后几个小时内，个人皮肤将产生最小红斑(因毛细血管充血引起的晒伤或红肿)的紫外线辐射量。本文介绍如何进行最小红斑剂量(MED)测试。如果不进行正式的MED测试，需要在测试后几个小时进行观察，或非正式的试验和错误测试，存在剂量不足或过量的风险，目前还没有简单的方法来确定用于临床或研究目的的适当紫外线剂量。然而，也讨论了一些替代方法。
Ultraviolet radiation (UV) therapy is sometimes used as a treatment for various common skin conditions, including psoriasis, acne, and eczema. The dosage of UV light is prescribed according to an individual's skin sensitivity. Thus, to establish the proper dosage of UV light to administer to a patient, the patient is sometimes screened to determine a minimal erythema dose (MED), which is the amount of UV radiation that will produce minimal erythema (sunburn or redness caused by engorgement of capillaries) of an individual's skin within a few hours following exposure. This article describes how to conduct minimal erythema dose (MED) testing. There is currently no easy way to determine an appropriate UV dose for clinical or research purposes without conducting formal MED testing, requiring observation hours after testing, or informal trial and error testing with the risks of under-or over-dosing. However, some alternative methods are discussed.