INTRAVASCULAR (CATHETER) NMR RECEIVER PROBE - PRELIMINARY DESIGN ANALYSIS AND APPLICATION TO CANINE ILIOFEMORAL IMAGING
INTRAVASCULAR (CATHETER) NMR RECEIVER PROBE - PRELIMINARY DESIGN ANALYSIS AND APPLICATION TO CANINE ILIOFEMORAL IMAGING
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DOI：
10.1002/mrm.1910240215
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发表时间：
1992-04-01
影响因子：
3.3
通讯作者：
COHEN, AM
中科院分区：
文献类型：
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作者：
HURST, GC;HUA, JM;COHEN, AM
本研究探讨了基于导管的接收器探头用于动脉壁NMR研究的可行性。模拟和体模实验证明了几种“内-外”探头线圈设计的空间响应，包括环路、“鸟笼”、“多极”、“中心返回”和反向线圈。对于由在垂直于B 0的平面中的环形限定的目标，相对螺线管设计提供了比所考虑的其它设计基本上上级的均匀性。在全身、1.5 T临床成像系统中使用导管探头采集犬髂股动脉图像。使用TE 70、TR 2400、2 mm层厚和78 × 78 μm面内体素尺寸在10 min采集时间内采集的原位（尸体）图像显示血管壁结构，包括内膜、内弹性膜、中膜、尽管使用了心脏门控和梯度矩归零，但来自类似采集条件的体内图像的分辨率要差得多，可能是由于运动，因此获得动脉壁的高分辨率体内MR图像的可行性仍然存在疑问。出版社：Academic Press，Inc.
This investigation explores the feasibility of a catheter‐based receiver probe for NMR study of arterial walls. Simulations and phantom experiments demonstrate the spatial response of several “inside‐out” probe coil designs, including loop, “birdcage,” “multipole,” “center return,” and opposed solenoids. For a target defined by an annulus in a plane perpendicular to B0, the opposed solenoid design provides substantially superior homogeneity to other designs considered. Canine iliofemoral artery images were acquired using a catheter probe in a whole‐body, 1.5‐T clinical imaging system.In situ(cadaver) images acquired with TE 70, TR 2400,2‐mm slice thickness, and 78 × 78‐μm in‐plane voxel size in 10‐min acquisition times show vessel wall structures identified as intima, internal elastic lamina, media, and adventitia.In vivoimages from similar acquisition conditions are much more poorly resolved, presumably due to motion, despite the use of cardiac gating and gradient moment nulling, so the feasibility of obtaining high‐resolutionin vivoMR images of the arterial wall remains in doubt. © 1992 Academic Press, Inc.