Production of FaeG, the major subunit of K88 fimbriae, in transgenic tobacco plants and its immunogenicity in mice
Production of FaeG, the major subunit of K88 fimbriae, in transgenic tobacco plants and its immunogenicity in mice
复制标题
DOI：
10.1128/iai.71.9.5436-5439.2003
复制
发表时间：
2003-09-01
影响因子：
3.1
通讯作者：
Zhang, DB
中科院分区：
文献类型：
--
作者：
Huang, YH;Liang, WQ;Zhang, DB
获得了稳定表达K88ad菌毛主要亚基和粘附素FaeG的转基因烟草植株。对免疫小鼠血清的分析表明，在小鼠中，植物来源的FaeG蛋白诱导的免疫原性与传统方法产生的免疫原性相当。
Transgenic tobacco plants stably expressing recombinant FaeG, which is the major subunit and adhesin of K88ad fimbriae, were obtained. Analysis of sera from immunized mice indicates that in mice, the immunogenicity induced by plant-derived FaeG protein is comparable to that generated with traditional approaches.