Anti-basal ganglia antibodies in patients with atypical dystonia and tics - A prospective study
Anti-basal ganglia antibodies in patients with atypical dystonia and tics - A prospective study
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DOI：
10.1212/01.wnl.0000131900.71337.c7
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发表时间：
2004-07-13
期刊：
影响因子：
9.9
通讯作者：
Bhatia, KP
中科院分区：
文献类型：
--
作者：
Edwards, MJ;Trikouli, E;Bhatia, KP
抗基底神经节抗体（ABGA）与儿童运动障碍有关，但尚未对成人运动障碍进行评估。在一项前瞻性评估中，65例非典型运动障碍患者中65%的ABGA呈阳性，但在健康成人和特发性肌张力障碍患者中非常罕见。自身免疫机制可能是部分非典型运动障碍病例的基础。
Anti-basal ganglia antibodies (ABGA) are associated with movement disorders in children, but have not been assessed in adult onset movement disorders. In a prospective assessment ABGA were positive in 65% of a group of 65 patients with atypical movement disorders, but were very rare in healthy adults and adults with idiopathic dystonia. An autoimmune mechanism may underlie a proportion of cases of atypical movement disorders.