Mutations in GCR3, a gene involved in the expression of glycolytic genes in Saccharomyces cerevisiae, suppress the temperature-sensitive growth of hpr1 mutants.

Mutations in GCR3, a gene involved in the expression of glycolytic genes in Saccharomyces cerevisiae, suppress the temperature-sensitive growth of hpr1 mutants.
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GCR3(一种参与酿酒酵母糖酵解基因表达的基因)的突变会抑制 hpr1 突变体的温度敏感生长。

DOI:
10.1093/genetics/142.4.1095
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发表时间:
1996
期刊:
影响因子:
3.3
通讯作者:
Sternglanz,R
Sternglanz,R
中科院分区:
生物学2区
文献类型:
--
作者:
Uemura,H;Pandit,S;Jigami,Y;Sternglanz,R

文献摘要

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通过分离anhprI top1-5双突变体的温度敏感生长抑制突变体,研究了DNA拓扑异构酶I和HprI蛋白的功能。抑制基因的克隆; GCR 3、HPR 1和TOP 1之间的遗传反应。
Presents a study in which the functions of DNA topoisomerase I and HprI protein were examined, through the isolation of a suppressor mutant of the temperature-sensitive growth of anhprI top1-5 double mutant. Cloning of suppressant gene; Genetic reactions between GCR3, HPR1 and TOP1.