Accounting for spin relaxation in quantitative pulse gradient spin echo NMR mixture analysis
Accounting for spin relaxation in quantitative pulse gradient spin echo NMR mixture analysis
复制标题
DOI：
10.1021/ja062592c
复制
发表时间：
2006-07-05
影响因子：
15
通讯作者：
Antalek, Brian
中科院分区：
文献类型：
--
作者：
Antalek, Brian
脉冲梯度自旋−回波(PGSE)核磁共振本质上是非定量的。由于实验是基于回声的，不同成分的原子核的弛豫行为的差异导致了不同的强度，并导致了非定量光谱。提出了一种通过处理几个不同延迟时间的PGSE核磁共振实验数据来恢复混合物的可分辨定量光谱的方法。该方法结合了一种简单的数据采集方案，并导致了计算快速的线性最小二乘分析。预计该方法将对聚合物溶液的混合物分析和表面修饰的纳米颗粒分散体的表征非常有兴趣。
Pulsed gradient spin−echo (PGSE) NMR is intrinsically nonquantitative. Because the experiment is echo-based, differences in the relaxation behavior of the nuclei among the components give rise to varied intensities and lead to nonquantitative spectra. A method is presented that restores resolved, quantitative spectra from mixtures by processing data from several PGSE NMR experiments with varied delay times. The approach incorporates a simple data acquisition scheme and leads to a computationally fast, linear least-squares analysis. It is anticipated the method will be of much interest for performing mixture analysis of polymer solutions and the characterization of surface-modified nanoparticulate dispersions.