The effectiveness of using e-cigarettes for quitting smoking compared to other cessation methods among adults in the United Kingdom

The effectiveness of using e-cigarettes for quitting smoking compared to other cessation methods among adults in the United Kingdom
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DOI:
10.1111/add.15474
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发表时间:
2021-05-04
期刊:
影响因子:
6
通讯作者:
Partos, Timea R.
Partos, Timea R.
中科院分区:
医学1区
文献类型:
--
作者:
McDermott, Mairtin S.;East, Katherine A.;Partos, Timea R.

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背景和目的关于电子烟(EC)促进戒烟的有效性的证据是有限的。目前的研究旨在估计的相对有效性相比,使用没有帮助,占频率的使用ECs.Design四个连续的波到波过渡(波1-2,2-3,3-4或4-5)的纵向在线调查收集2012年和2017年进行了分析。波之间的时间范围为12至17个月。在基线波吸烟者谁试图戒烟波之间也包括在内。设置英国参与者共1155名受访者(年龄18-81岁,56.1%男性,64.6%社会等级C2 DE,93.8%白色)提供了1580对观察结果用于初步分析。次要结局:基线和随访之间戒烟至少1个月。主要预测因素是戒烟辅助剂的使用(没有帮助,尼古丁替代治疗,戒烟药物,一次性/墨盒EC,笔芯/模块EC,组合),调整人口统计学。结果主要相比,使用没有帮助,戒烟的几率增加了每天使用一次性/墨盒EC(OR = 3.31(1.32,8.26),P = 0.010)和每日使用再填充/模块化EC(OR = 5.47(2.70,11.11),P <0.001)。非每日使用一次性/盒式EC(OR = 0.23(0.08-0.63),P = 0.005),以及使用一次性/盒式EC退出并在随访时不再使用(OR = 0.10(0.16-0.62),P <0.013)的几率降低。次要结果与主要结果相似;然而,使用戒烟药物也增加了戒烟的几率(OR = 4.15(1.79,9.62),P = .001)。结论:与不使用帮助相比,每天使用电子烟似乎有助于戒烟。
Background and aims Evidence on the effectiveness of electronic cigarettes (ECs) to facilitate abstinence from smoking is limited. The current study aimed to estimate the relative effectiveness of ECs and smoking cessation medication compared with using no help, accounting for frequency of use of ECs.Design Four consecutive wave-to-wave transitions (waves 1-2, 2-3, 3-4 or 4-5) of a longitudinal online survey collected between 2012 and 2017 were analysed. Time between waves ranged between 12 and 17 months. Cigarette smokers at the baseline wave who attempted to quit smoking between waves were included.Setting United KingdomParticipants A total of 1155 respondents (aged 18-81, 56.1% male, 64.6% in social grade C2DE, 93.8% white) provided 1580 pairs of observations for the primary analysis.Measurements Primary outcome: abstinence from smoking for at least 1 month at follow-up; secondary outcome: at least 1 month's abstinence from smoking between baseline and follow-up. The main predictor was stop smoking aid used (No help, nicotine replacement therapy only, smoking cessation medication only, disposable/cartridge EC, refill/modular EC, combination), adjusted for demographics.Findings Primary Compared with using no help, the odds of abstinence were increased by daily use of disposable/cartridge ECs (OR = 3.31 (1.32, 8.26), P = .010) and daily use of refill/modular ECs (OR = 5.47 (2.70, 11.11), P < .001). Odds were reduced by non-daily use of disposable/cartridge ECs (OR = 0.23 (0.08-0.63), P = .005), and by use of disposable/cartridge ECs to quit and no longer using at follow-up (OR = 0.10 (0.16-0.62), P < .013). Secondary Results were similar to the primary outcome; however, odds of abstinence were also increased by use of smoking cessation medication (OR = 4.15 (1.79, 9.62), P = .001).Conclusions When used daily, electronic cigarettes appear to facilitate abstinence from smoking when compared with using no help.