ArrayExpress update--from an archive of functional genomics experiments to the atlas of gene expression.

ArrayExpress update--from an archive of functional genomics experiments to the atlas of gene expression.
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DOI:
10.1093/nar/gkn889
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发表时间:
2009-01
影响因子:
14.9
通讯作者:
Brazma A
Brazma A
中科院分区:
生物学2区
文献类型:
--
作者:
Parkinson H;Kapushesky M;Kolesnikov N;Rustici G;Shojatalab M;Abeygunawardena N;Berube H;Dylag M;Emam I;Farne A;Holloway E;Lukk M;Malone J;Mani R;Pilicheva E;Rayner TF;Rezwan F;Sharma A;Williams E;Bradley XZ;Adamusiak T;Brandizi M;Burdett T;Coulson R;Krestyaninova M;Kurnosov P;Maguire E;Neogi SG;Rocca-Serra P;Sansone SA;Sklyar N;Zhao M;Sarkans U;Brazma A

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ArrayExpress http://www.ebi.ac.uk/arrayexpress由三个组件组成:ArrayExpress存储库 - 功能基因组学实验的公共档案馆和支持数据,一个ArrayExpress Warehouse,ArrayExpress Warehouse,一个基因表达和其他生物测量的数据库, Array Express Atlas - 跨多个实验和不同的生物条件的新的摘要数据库和元分析工具。存储库包含超过6000个实验的数据,完成了大约200万种测定法数据中的数据是基于数组的,但最近包括其他数据类型 - 乌尔特(Ultra)高通量测序转录组学和表观遗传学数据。 ,或两者的组合。
ArrayExpress http://www.ebi.ac.uk/arrayexpress consists of three components: the ArrayExpress Repository—a public archive of functional genomics experiments and supporting data, the ArrayExpress Warehouse—a database of gene expression profiles and other bio-measurements and the ArrayExpress Atlas—a new summary database and meta-analytical tool of ranked gene expression across multiple experiments and different biological conditions. The Repository contains data from over 6000 experiments comprising approximately 200 000 assays, and the database doubles in size every 15 months. The majority of the data are array based, but other data types are included, most recently—ultra high-throughput sequencing transcriptomics and epigenetic data. The Warehouse and Atlas allow users to query for differentially expressed genes by gene names and properties, experimental conditions and sample properties, or a combination of both. In this update, we describe the ArrayExpress developments over the last two years.