A TOTAL SYNTHESIS OF DRAGMACIDIN-B

A TOTAL SYNTHESIS OF DRAGMACIDIN-B
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DOI:
10.1016/0040-4039(94)85056-9
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发表时间:
1994-01-17
影响因子:
1.8
通讯作者:
CAVA, MP
CAVA, MP
中科院分区:
化学4区
文献类型:
--
作者:
WHITLOCK, CR;CAVA, MP

文献摘要

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本文报道了一种简单的全合成方法-龙霉素B。这构成了海洋生物碱的2,5-双(3 '-吲哚基)哌嗪家族成员的首次合成。还制备了双脱溴的dragmacidin B类似物。
A simple total synthesis of dragmacidin B is described. This constitutes the first synthesis of a member of the 2,5-bis(3'-indoly)piperazine family of marine alkaloids. The didebromo analog of dragmacidin B was also prepared.