Protein-affinity of single-walled carbon nanotubes in water
Protein-affinity of single-walled carbon nanotubes in water
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DOI：
10.1021/jp031248o
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发表时间：
2004-03-25
影响因子：
3.3
通讯作者：
Sun, YP
中科院分区：
文献类型：
--
作者：
Lin, Y;Allard, LF;Sun, YP
研究了单壁碳纳米管与铁蛋白在水中的相互作用。发现单壁碳纳米管在铁蛋白水溶液中是天然的蛋白亲和性的，导致显著的铁蛋白-单壁碳纳米管缀合和碳纳米管的溶解。在存在用于酰胺化的偶联剂以促进共价键的形成的情况下，进一步增强和稳定缀合。SWNT的天然蛋白质亲和性可以通过用亲水性聚合物或更好地用低聚聚（乙二醇）部分官能化纳米管来减轻或甚至消除。
The interactions of single-walled carbon nanotubes (SWNTs) with ferritin protein in water were investigated. It was found that SWNTs are naturally protein-affinitive in an aqueous ferritin solution, resulting in significant ferritin-SWNT conjugation and the solubilization of the nanotubes. The conjugation is further enhanced and stabilized in the presence of a coupling agent for amidation to promote the formation of covalent linkages. The natural protein-affinity of SWNTs may be alleviated or even eliminated by the functionalization of the nanotubes with hydrophilic polymers or better with oligomeric poly(ethylene glycol) moieties.