THE EFFECTS OF DUAL TASKING ON HANDWRITING IN PATIENTS WITH PARKINSON'S DISEASE
THE EFFECTS OF DUAL TASKING ON HANDWRITING IN PATIENTS WITH PARKINSON'S DISEASE
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DOI：
10.1016/j.neuroscience.2014.01.019
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发表时间：
2014-03-28
期刊：
影响因子：
3.3
通讯作者：
Heremans, E.
中科院分区：
文献类型：
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作者：
Broeder, S.;Nackaerts, E.;Heremans, E.
先前的研究表明，帕金森病 (PD) 患者在执行双重任务时会遇到广泛的问题。到目前为止，PD 中的双任务干扰主要是在步态研究的背景下进行的。然而，同时执行两项不同的任务也是有效执行日常生活中许多其他任务（包括上肢任务）的先决条件。为了解决这个问题，本研究调查了次要认知任务对帕金森病患者书写能力的影响。 18 名 PD 患者和 11 名年龄匹配的对照者执行了一项写作任务，涉及在单任务和双任务条件下产生重复循环。第二项任务包括在书写过程中计算高音和低音。使用书写板以两个幅度（0.6 和 1.0 厘米）进行书写测试。结果显示，与对照组相比，PD 患者的双重任务表现受到影响。双重任务减少了帕金森病患者的书写幅度，但在健康对照中却没有（p = 0.046）。患者的书写尺寸主要在小振幅条件下减少（小振幅 p = 0.017；大振幅 p = 0.310）。这表明，在 PD 中，小幅度写入的控制需要更多补偿性大脑处理资源，因此比大幅度写入的自动化程度低。此外，与对照组相比，PD 患者对次要任务的双重任务效应更大 (p = 0.025)。通过“手写困难系统筛查”测试（SOS 测试）和其他手工灵活性任务，特别是在双任务条件下测量，书写板上的书写测试与日常生活书写高度相关。总而言之，这些结果为帕金森病患者的手写运动控制和上肢运动过程中双重任务的影响提供了更多见解。 (C) 2014 年国际广播组织。由爱思唯尔有限公司出版。保留所有权利。
Previous studies have shown that patients with Parkinson's disease (PD) experience extensive problems during dual tasking. Up to now, dual-task interference in PD has mainly been investigated in the context of gait research. However, the simultaneous performance of two different tasks is also a prerequisite to efficiently perform many other tasks in daily life, including upper limb tasks. To address this issue, this study investigated the effect of a secondary cognitive task on the performance of handwriting in patients with PD. Eighteen PD patients and 11 age-matched controls performed a writing task involving the production of repetitive loops under single- and dual-task conditions. The secondary task consisted of counting high and low tones during writing. The writing tests were performed with two amplitudes (0.6 and 1.0 cm) using a writing tablet. Results showed that dual-task performance was affected in PD patients versus controls. Dual tasking reduced writing amplitude in PD patients, but not in healthy controls (p = 0.046). Patients' writing size was mainly reduced during the small-amplitude condition (small amplitude p = 0.017; large amplitude p = 0.310). This suggests that the control of writing at small amplitudes requires more compensational brain-processing recourses in PD and is as such less automatic than writing at large amplitudes. In addition, there was a larger dual-task effect on the secondary task in PD patients than controls (p = 0.025). The writing tests on the writing tablet proved highly correlated to daily life writing as measured by the 'Systematic Screening of Handwriting Difficulties' test (SOS-test) and other manual dexterity tasks, particularly during dual-task conditions. Taken together, these results provide additional insights into the motor control of handwriting and the effects of dual tasking during upper limb movements in patients with PD. (C) 2014 IBRO. Published by Elsevier Ltd. All rights reserved.