Multisensory auditory-somatosensory interactions in early cortical processing revealed by high-density electrical mapping
Multisensory auditory-somatosensory interactions in early cortical processing revealed by high-density electrical mapping
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DOI：
10.1016/s0926-6410(00)00024-0
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发表时间：
2000-09-01
期刊：
影响因子：
--
通讯作者：
Schroeder, CE
中科院分区：
文献类型：
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作者：
Foxe, JJ;Morocz, IA;Schroeder, CE
我们研究了人类同时听觉和体感刺激之间多感觉相互作用的时程和头皮地形图。在头皮电极上记录事件相关电位(ERP)，分别给予听觉单独刺激(1000 Hz纯音)、躯体感觉单独刺激(正中神经电脉冲)和同时听觉-躯体感觉(AS)联合刺激。通过比较组合刺激的反应与单独呈现听觉和躯体感觉刺激时的反应的代数和来评估交互效应。对ERPs和头皮电流密度(SCD)地形图的时空分析显示，中央/中央后中央头皮上的相互作用大约在刺激后50ms开始。在传统上被认为是单一感觉的大脑区域中，这些相互作用的地形和时间都与大脑皮层处理层级早期的多感觉整合相一致。(C)2000 Elsevier Science B.V.保留所有权利。
We investigated the time-course and scalp topography of multisensory interactions between simultaneous auditory and somatosensory stimulation in humans. Event-related potentials (ERPs) were recorded from 64 scalp electrodes while subjects were presented with auditory-alone stimulation (1000-Hz tones), somatosensory-alone stimulation (median nerve electrical pulses), and simultaneous auditory-somatosensory (AS) combined stimulation. Interaction effects were assessed by comparing the responses to combined stimulation with the algebraic sum of responses to the constituent auditory and somatosensory stimuli when they were presented alone. Spatiotemporal analysis of ERPs and scalp current density (SCD) topographies revealed AS interaction over the central/postcentral scalp which onset at approximately 50 ms post-stimulus presentation. Both the topography and timing of these interactions are consistent with multisensory integration early in the cortical processing hierarchy, in brain regions traditionally held to be unisensory. (C) 2000 Elsevier Science B.V. All rights reserved.