Human cerebellum: Surface-assisted cortical parcellation and volumetry with magnetic resonance imaging

Human cerebellum: Surface-assisted cortical parcellation and volumetry with magnetic resonance imaging
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DOI:
10.1162/089892903321662967
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发表时间:
2003-05-15
影响因子:
3.2
通讯作者:
Schmahmann, JD
Schmahmann, JD
中科院分区:
医学3区
文献类型:
--
作者:
Makris, N;Hodge, SM;Schmahmann, JD

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我们描述了一种源自神经系统功能和行为解剖学的人类小脑皮层表面辅助包裹(SAP)系统。该系统以MRI为基础,保留了个体小脑的独特形态和地形特征。所有小脑的主要裂缝都是用“FreeSurfer”程序在小脑皮层的扁平表示中识别和追踪的。使用“Cardviews”程序将裂缝信息与地标相结合,然后对小脑皮层进行分割,以创建64个基于脑回的小脑分割单元。计算机辅助算法能够执行小脑包裹程序以及体积测量和地形定位。SAP技术使得在小脑皮层的平坦表面上表示多模态结构和功能成像数据成为可能,如一个功能性MRI实验所示。
We describe a system of surface-assisted parcellation (SAP) of the human cerebellar cortex derived from neural systems functional and behavioral anatomy. This system is based on MRI and preserves the unique morphologic and topographic features of the individual cerebellum. All major fissures of the cerebellum were identified and traced in the flattened representation of the cerebellar cortex using the program "FreeSurfer." Parcellation of the cerebellar cortex followed using the fissure information in conjunction with landmarks using the program "Cardviews" to create 64 gyral-based cerebellar parcellation units. Computer-assisted algorithms enable the execution of the cerebellar parcellation procedure as well as volumetric measurements and topographic localization. The SAP technique makes it possible to represent multimodal structural and functional imaging data on the flattened surface of the cerebellar cortex as illustrated in one functional MRI experiment.