Treatment for apraxia of speech in nonfluent variant primary progressive aphasia
Treatment for apraxia of speech in nonfluent variant primary progressive aphasia
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DOI：
10.3233/ben-2012-120260
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发表时间：
2013-01-01
影响因子：
2.8
通讯作者：
Gorno-Tempini, M. L.
中科院分区：
文献类型：
--
作者：
Henry, M. L.;Meese, M. V.;Gorno-Tempini, M. L.
越来越多的文献研究了行为治疗在原发性进行性失语症（PPA）中的应用。然而，目前还没有研究探索改善与PPA不流利变体相关的言语失用（AOS）患者的言语产生的治疗方法。本研究的目的是研究一种治疗不流利PPA患者AOS的新方法。我们实施了一种治疗方法，将结构化口语阅读作为一种工具，用于改善轻度AOS和不流利变体PPA患者多音节单词的产生。我们的参与者在阅读小说文本时的言语错误减少，这种情况在治疗后一年内保持不变。在单词和句子的重复中观察到改善的语音生成的泛化，并且在连接语音中表现出随时间的稳定性。结果表明，口语阅读治疗可能是解决不流利PPA相关的AOS多音节单词产生的有效方法，具有持久和广泛的治疗效果。
There is a growing body of literature examining the utility of behavioral treatment in primary progressive aphasia (PPA). There are, however, no studies exploring treatment approaches to improve speech production in individuals with apraxia of speech (AOS) associated with the nonfluent variant of PPA. The purpose of this study was to examine a novel approach to treatment of AOS in nonfluent PPA. We implemented a treatment method using structured oral reading as a tool for improving production of multisyllabic words in an individual with mild AOS and nonfluent variant PPA. Our participant showed a reduction in speech errors during reading of novel text that was maintained at one year post-treatment. Generalization of improved speech production was observed on repetition of words and sentences and the participant showed stability of speech production over time in connected speech. Results suggest that oral reading treatment may offer an efficient and effective means of addressing multisyllabic word production in AOS associated with nonfluent PPA, with lasting and generalized treatment effects.