Risks of acquiring and transmitting sexually transmitted diseases in sexual partner networks

Risks of acquiring and transmitting sexually transmitted diseases in sexual partner networks
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DOI:
10.1097/00007435-200011000-00006
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发表时间:
2000-11-01
影响因子:
3.1
通讯作者:
Garnett, GP
Garnett, GP
中科院分区:
医学4区
文献类型:
--
作者:
Ghani, AC;Garnett, GP

文献摘要

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背景资料:一个人感染的风险及其在持续传播中的作用传统上是根据个人特征进行评估的。最近,网络研究试图将个人风险与更广泛的网络中的位置联系起来。目标:评估局部和全球网络结构在评估获得和传播感染风险中的重要性。研究设计:使用基于个人的模拟模型构建各种潜在的网络结构,并跟踪感染随时间的传播。Logistic和Poisson回归用于确定哪些网络位置的措施影响一个人的获得和传播感染的风险。结果:本地中心性的措施更重要的收购风险,而全球中心性更重要的传播。连续的雪球采样,而不是一个固定数量的波,更好地估计一个人的risks.Conclusions:有一个关于获得和传播感染的风险不对称。
Background: A person's risk for acquiring infection and their role in continued transmission has traditionally been assessed on the basis of individual characteristics. Recently, network studies have attempted to relate individual risks to position in the wider network.Goal: To assess the importance of local and global network structures in assessing the risk of acquiring and transmitting infection.Study Design: An individual-based simulation model was used to construct a variety of potential network structures and track the transmission of infection over time. Logistic and Poisson regression were used to identify which measures of network position influence a person's risk for acquiring and transmitting infection,Results: Measures of local centrality were more important to risk of acquisition, whereas global centrality mattered more to transmission. Continuous snowball sampling, rather than a fixed number of waves, better estimates a person's risks.Conclusions: There is an asymmetry regarding the risk of acquiring and transmitting infection.