Reflections on the rise in asthma morbidity and mortality.

Reflections on the rise in asthma morbidity and mortality.
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对哮喘发病率和死亡率上升的思考。

DOI:
10.1001/jama.1990.03450130091034
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发表时间:
1990
期刊:
JAMA
影响因子:
--
通讯作者:
W. Vollmer
W. Vollmer
中科院分区:
--
文献类型:
--
作者:
A. Buist;W. Vollmer

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在美国和许多其他西方国家,哮喘的发病率和死亡率似乎在增加。1 - 7这种常见疾病的患病率也可能在增加。8,9这些趋势令人担忧,因为它们发生在许多慢性疾病的发病率和死亡率正在下降的时候,当我们认为我们对哮喘的病理生理学有相当好的理解时,当我们相信我们有更有效的药物来治疗它的时候。从1965年到1978年,美国和加拿大的哮喘死亡率下降,然后又开始上升。从1980年到1987年,美国死于哮喘的总人数从2891人增加到4360人。3这意味着死亡率增加了31%,从1.3/10万人口增加到1.7/10万人口。女性的死亡率比男性增长得更快,
Morbidity and mortality for asthma appear to be on the increase in the United States and many other Western countries.1-7The prevalence of this common condition may also be increasing.8,9These trends are worrisome, because they come at a time when morbidity and mortality from many chronic diseases are decreasing, when we think we have a fairly sound understanding of the pathophysiology of asthma, and when we believe we have more effective drugs for its management. Asthma mortality rates declined in the United States and Canada from 1965 through 1978 and then started to rise again. From 1980 to 1987, total deaths from asthma in the United States increased from 2891 to 4360.3 This represents a 31% increase in the death rate, from 1.3/100 000 population to 1.7/100 000. The rate for females increased more rapidly than the rate for males, and death rates were generally higher for