MOLECULAR-CLONING OF THE CD2 ANTIGEN, THE T-CELL ERYTHROCYTE RECEPTOR, BY A RAPID IMMUNOSELECTION PROCEDURE
MOLECULAR-CLONING OF THE CD2 ANTIGEN, THE T-CELL ERYTHROCYTE RECEPTOR, BY A RAPID IMMUNOSELECTION PROCEDURE
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DOI：
10.1073/pnas.84.10.3365
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发表时间：
1987-05-01
影响因子：
11.1
通讯作者：
ARUFFO, A
中科院分区：
文献类型：
--
作者：
SEED, B;ARUFFO, A
A cDNA encoding the CD2 antigen has been isolated by a highly efficient technique based on transient expression in COS cells and adherence of cells expressing surface antigen to antibody-coated dishes. COS cells expressing a CD2 cDNA isolated by this method readily formed rosettes with sheep as well as human and other mammalian erythrocytes. Pretreatment of transfected COS cells with anti-CD2 antibody, or pretreatment of human erythrocytes with anti-LFA-3 antibody, abolished rosette formation.
