Autoregulation of retinal blood flow in diabetic retinopathy measured by the blue-light entoptic technique.
Autoregulation of retinal blood flow in diabetic retinopathy measured by the blue-light entoptic technique.
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通过蓝光内视技术测量糖尿病视网膜病变中视网膜血流的自动调节。
DOI：
10.1016/s0161-6420(87)33271-3
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发表时间：
1987
期刊：
影响因子：
13.7
通讯作者：
E. Kohner
中科院分区：
文献类型：
--
作者：
T. Fallon;D. Maxwell;E. Kohner
对23例糖尿病患者，9例非增殖性视网膜病变，9例增殖性视网膜病变和5例光凝性视网膜病变进行了视网膜血流自动调节测定。三个增殖患者进行了研究，在两个场合，在增殖阶段和光凝后。所用的自动调节刺激是等二氧化碳高氧和缺氧。使用蓝视野内视镜技术测量中心凹周围循环中白细胞的流速，并使用计算机数字化系统测量视网膜动脉和静脉直径。结果在等二氧化碳缺氧条件下，非增生性视网膜病变组平均血流速度增加41.0 ± 33.0%（P< 0.05），增生性视网膜病变组平均血流速度增加3.5 ± 17.0%（P <0.05），光凝后平均血流速度增加30.0 ± 17.0%（P< 0.05）。在高氧时，非增殖性视网膜病变的血流速度平均下降21.0 ± 21.6%（P< 0.05），增殖性视网膜病变下降33.0 ± 19.9%（P< 0.005），光凝性视网膜病变下降21.0 ± 26.0%（无显著性）。结果进行了比较，与一组非糖尿病受试者先前报道。
Autoregulation of retinal blood flow was measured in 23 diabetic patients, 9 with nonproliferative retinopathy, 9 with proliferative retinopathy, and 5 with photocoagulated retinopathy. Three of the proliferative patients were studied on two occasions, at the proliferative stage and after photocoagulation. The stimuli to autoregulation used were isocapnic hyperoxia and hypoxia. Flow velocity of leukocytes in the perifoveal circulation was measured using the blue-field entoptic technique, and retinal artery and vein diameters were measured using a computerized digitizing system. Results under conditions of isocapnic hypoxia showed a mean increase in flow velocity of 41.0 ± 33.0% (P< 0.05) in nonproliferative retinopathy, 3.5 ± 17.0% (not significant) in proliferative retinopathy, and 30.0 ± 17.0% (P< 0.05) after photocoagulation. In hyperoxia, flow velocity fell by a mean of 21.0 ± 21.6% (P< 0.05) in nonproliferative retinopathy, 33.0 ± 19.9% (P< 0.005) in proliferative retinopathy, and 21.0 ± 26.0% (not significant) in photocoagulated retinopathy. The results are compared with a group of nondiabetic subjects reported previously.
改变%20视网膜%20血管%20反应%20至%20100%%20氧气%20呼吸%20in%20糖尿病%20。
影响因子：
13.7
作者：
Grunwald,JE;Riva,CE;Brucker,AJ;Sinclair,SH;Petrig,BL
通讯作者：
Petrig,BL
激光多普勒测速研究纯氧呼吸对视网膜血流的影响。
影响因子：
4.4
作者：
Riva,CE;Grunwald,JE;Sinclair,SH
通讯作者：
Sinclair,SH