PRECISE CHARACTERIZATION AND QUANTIFICATION OF INFANTILE SPASMS
PRECISE CHARACTERIZATION AND QUANTIFICATION OF INFANTILE SPASMS
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DOI：
10.1002/ana.410060306
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发表时间：
1979-01-01
影响因子：
11.2
通讯作者：
ZION, T
中科院分区：
文献类型：
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作者：
KELLAWAY, P;HRACHOVY, RA;ZION, T
通过使用时间同步视频和多导记录系统，对24名1至43个月的婴儿中的5，042例婴儿痉挛进行了监测和分析。其中，33.9%为屈肌，22.5%为伸肌，42.0%为混合屈肌-伸肌。有时痉挛之后会出现一段时间的运动不能和反应性减弱，持续时间长达90秒，很少（1.0%）这种“阻滞”效应构成整个癫痫发作。24名婴儿中有21名发生了一种以上的癫痫发作。在相同的数量中，78.3%的癫痫发作发生在集群中，每个集群中痉挛的强度和频率通常增加到一个峰值，然后逐渐下降，直到停止。大多数情况下，集群发生后不久从睡眠中唤醒。夜间发作次数（55.2%）与白天发作次数（44.8%）相似。脑电图癫痫发作模式是可变的，但一个显着的广泛衰减的电活动是一个功能的71.7%的攻击。发生相似程度和持续时间的衰减发作，无癫痫发作证据。
With the use of a time‐synchronized video and polygraphic recording system, 5,042 infantile spasms were monitored and analyzed in 24 infants aged 1 to 43 months. Of these, 33.9% were flexor, 22.5% extensor, and 42.0% mixed flexor‐extensor. Sometimes the spasms were followed by a period of akinesia and diminished responsiveness lasting up to 90 seconds, and rarely (1.0%) this “arrest” effect constituted the entire seizure. More than one type of seizure occurred in 21 of the 24 infants. In the same number, 78.3% of the seizures occurred in clusters, and the intensity and frequency of the spasms in each cluster often increased to a peak, then progressively decreased until they stopped. Predominantly, the clusters occurred soon after arousal from sleep. The number of seizures occurring at night (55.2%) was similar to the diurnal number (44.8%). The electroencephalographic seizure pattern was variable, but a marked generalized attenuation of electrical activity was a feature of 71.7% of the attacks. Attenuation episodes of similar degree and duration occurred with no evidence of a seizure.