A multivariable model for predicting the need for blood transfusion in patients undergoing first-time elective coronary bypass graft surgery
A multivariable model for predicting the need for blood transfusion in patients undergoing first-time elective coronary bypass graft surgery
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DOI：
10.1046/j.1537-2995.2001.41101193.x
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发表时间：
2001-10-01
期刊：
影响因子：
2.9
通讯作者：
Sher, GD
中科院分区：
文献类型：
--
作者：
Karkouti, K;Cohen, MM;Sher, GD
背景：冠状动脉旁路移植(CABG)手术中输血的发生率仍然很高，术前识别那些需要输血的高危人群将使一些血液保护措施的使用变得经济有效。研究设计与方法：前瞻性收集1997年1月至1998年9月在三级护理教学医院接受择期冠状动脉搭桥术的所有患者的数据(n=1007)。预测规则是通过使用Logistic回归方法在样本的前三分之二上制定的，以检查患者人口统计学、合并症和术前Hb与围手术期输血的关系。其余三分之一的样本用于验证规则。结果：输血率为29.4%。预测规则包括术前Hb(g/dL，OR 0.928，p
BACKGROUND: The incidence of blood transfusion in coronary artery bypass graft (CABG) surgery remains high, Preoperative identification of those at high risk for requiring blood will allow for the cost-effective use of some blood conservation modalities. Multivariable analysis techniques were used in this study to develop a prediction rule for such a purpose.STUDY DESIGN AND METHODS: Data were prospectively collected for all patients undergoing elective first-time CABG surgery from January 1997 to September 1998 at a tertiary-care teaching hospital (n = 1007). The prediction rule was developed on the first two-thirds of the sample by using logistic regression methods to examine the relationship of patient demographics, comorbidities, and preoperative Hb with perioperative blood transfusion. The remaining one-third of the sample was used to validate the rule.RESULTS: The transfusion rate was 29.4 percent. The prediction rule included preoperative Hb (g/dL, OR 0.928, p