RELATIONS FOR LIPID BILAYERS - CONNECTION OF ELECTRON-DENSITY PROFILES TO OTHER STRUCTURAL QUANTITIES
RELATIONS FOR LIPID BILAYERS - CONNECTION OF ELECTRON-DENSITY PROFILES TO OTHER STRUCTURAL QUANTITIES
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DOI：
10.1016/s0006-3495(89)82806-1
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发表时间：
1989-02-01
影响因子：
3.4
通讯作者：
WIENER, MC
中科院分区：
文献类型：
--
作者：
NAGLE, JF;WIENER, MC
导出了三个关系式，将从脂质双层得到的低角衍射/散射结果与其他感兴趣的结构量联系起来。第一个涉及沿双层表面的面积、测量的比体积和零级结构因子F(0)。第二种与电子密度分布中心的槽的大小、末端甲基的体积和脂肪酸链中亚甲基的体积有关。第三种是头基团电子密度峰的大小、头基团的体积以及头基区的水和烃的体积。这些关系式很容易对中子衍射进行修正，对于从电子密度分布中获得结构量是有用的，这些电子密度分布是通过将模型分布与测量的小角X射线强度进行拟合而获得的。
Three relations are derived that connect low angle diffraction/scattering results obtained from lipid bilayers to other structural quantities of interest. The first relates the area along the surface of the bilayer, the measured specific volume, and the zeroth order structure factor, F(0). The second relates the size of the trough in the center of the electron density profile, the volume of the terminal methyl groups, and the volume of the methylene groups in the fatty acid chains. The third relates the size of the headgroup electron density peak, the volume of the headgroup, and the volumes of water and hydrocarbon in the headgroup region. These relations, which are easily modified for neutron diffraction, are useful for obtaining structural quantities from electron density profiles obtained by fitting model profiles to measured low angle x-ray intensities.