Does breast-feeding influence intelligence quotients at 9 and 10 years of age?

Does breast-feeding influence intelligence quotients at 9 and 10 years of age?
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DOI:
10.1016/s0378-3732(97)00044-1
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发表时间:
1998-01-09
影响因子:
2.5
通讯作者:
Berendes, H
Berendes, H
中科院分区:
医学4区
文献类型:
--
作者:
Malloy, MH;Berendes, H

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母乳喂养对智力发展的影响仍然存在争议。我们在高社会经济人群中探索了这种关系,在这些人群中,母乳喂养在生命的第一年的某个时候补充了含有大豆的配方奶粉。1988年,国家儿童健康和人类发展研究所对华盛顿特区的两个大都市进行了以学校为基础的调查,以确定1978年至1979年出生队列中在婴儿时期接触过氯化物缺乏配方的Neo-Mull-Soy和Cho-Free配方的儿童,作为调查的一部分,研究人员还获得了接触过氯化物缺乏配方的儿童和一组接触过其他大豆配方的对照组儿童的母乳喂养信息。由于没有观察到两组儿童在智力发展方面的差异,因此将它们结合起来,评估母乳喂养对9岁和10岁儿童智力发展的影响。176名婴儿没有接受母乳喂养,342名婴儿接受母乳喂养。母乳喂养的中位持续时间为124天(四分位数范围为42-248天)。母乳喂养和非母乳喂养的婴儿在出生体重、性别和种族方面没有差异。母乳喂养的婴儿的平均韦斯切勒智力量表(修订完整量表)智商为122,而非母乳喂养的婴儿的平均智商为118 (P = 0.0008)。然而,在对母亲教育程度、父亲教育程度和年收入进行线性回归调整后,母乳喂养的平均全面智商为111,非母乳喂养的平均全面智商为110 (P = 0.23)。进一步的分析仅限于前60天纯母乳喂养的婴儿,未能证明母乳喂养与智商之间有任何显著关系。(C) 1998爱思唯尔科学爱尔兰有限公司
The effect of breast-feeding on intellectual development remains controversial. We explored this relationship in a high socioeconomic population in which breast feeding was supplemented with soy containing formulas at some time during the first year of life. As part of the 1988 National Institute of Child Health and Human Development school-based survey of two metropolitan Washington, D.C. counties to identify children in the 1978 to 1979 birth cohort who had been exposed to the chloride deficient formulas Neo-Mull-Soy and Cho-Free during infancy, information on breast-feeding was also obtained on children exposed to the chloride-deficient formulas and a group of control children exposed to other soy formulas. Because no differences in intellectual development were observed between the two groups, they were combined and the effect of breast-feeding on intellectual development at 9 and 10 years was assessed. There were 176 infants that received no breast-feeding and 342 who were breast-fed. The median duration of breast feeding was 124 days (interquartile range, 42-248 days). There were no differences in birth weight, gender or race between the infants who were breast-fed and those who were not. The mean Weschler Intelligence Scale-Revised Full Scale IQ was 122 among those breast-fed compared to 118 among those that were not (P = 0.0008). However, following adjustment by Linear regression for maternal education, paternal education and annual income the adjusted mean full scale IQ was 111 among the breast-fed and 110 among the non-breast-fed (P = 0.23). Further analyses limited to those exclusively breast-fed for the first 60 days failed to demonstrate any significant relationship between breast-feeding and IQ. (C) 1998 Elsevier Science Ireland Ltd.