Sources of heterogeneities in estimating the prevalence of endometriosis in infertile and previously fertile women
Sources of heterogeneities in estimating the prevalence of endometriosis in infertile and previously fertile women
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DOI：
10.1016/j.fertnstert.2006.04.040
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发表时间：
2006-12-01
影响因子：
6.7
通讯作者：
Wang, Yuedong
中科院分区：
文献类型：
--
作者：
Guo, Sun-Wei;Wang, Yuedong
目的：为了确定可能的来源的异质性估计的患病率子宫内膜异位症在以前的生育妇女和不孕women with infertility.Design：汇总分析以前发表的研究报告患病率估计设置：学术患者：无干预措施：无主要结果措施：无结果：有巨大的异质性在患病率估计为生育和不育组。此外，患病率估计值随发表年份的增加而增加，但随样本量的增加而减少。对于既往有生育能力的妇女，在考虑样本量和发表年份对估计值的影响后，患病率估计值的异质性不再显著。然而，在不育组中，仍然是一个相当大的异质性未占后，样本量和年的出版considered.Conclusions：一个单一的患病率估计，为整个生育或不育组可能过于简单化。更精确的患病率估计，可能是年龄依赖性的，等待精心设计和执行的研究，也将记录协变量，如手术年龄和转诊模式。
Objective: To identify possible sources of heterogeneity in estimates of the prevalence of endometriosis in previously fertile women and in women with infertility.Design: A pooled analysis of previously published studies reporting prevalence estimates.Setting: Academic.Patients: None.Interventions: None.Main Outcome Measures: None.Results: There were tremendous heterogeneities in prevalence estimates for both the fertile and infertile groups. in addition, the prevalence estimates increased with the ear of publication, but decreased with sample size size For previously fertile women, the heterogeneity in prevalence estimates was no longer significant after the effects of sample size and year of publication on estimates were taken into account. In the infertile group, however, there. was still a sizeable heterogeneity unaccounted for after both sample size and year of publication were taken into account.Conclusions: A single prevalence estimate, for the entire-fertile or infertile group may be too simplistic at best. More precise prevalence estimates, likely to be age-dependent, await carefully designed and executed studies that will also record covariates such as age at surgery and referral patterns.