Pilot study of a point-of-use decision support tool for cancer clinical trials eligibility
Pilot study of a point-of-use decision support tool for cancer clinical trials eligibility
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DOI：
10.1136/jamia.1999.0060466
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发表时间：
1999-11-01
影响因子：
6.4
通讯作者：
Tierney, WM
中科院分区：
文献类型：
--
作者：
Breitfeld, PP;Weisburd, M;Tierney, WM
许多患有癌症的成年人没有参加临床试验，因为护理人员没有时间将患者的临床结果与患者可能有资格参加的多项试验相关的不同资格标准进行匹配。作者开发了一种使用点便携式决策支持工具 (DS-TRIEL) 来自动化此匹配过程。支持工具由带有可编程关系数据库的手持计算机组成。使用两级分层决策框架来确定两项开放乳腺癌临床试验的合格受试者。手持式计算机还提供协议同意书和模式，以进一步帮助忙碌的肿瘤科医生。该决策支持工具及其所依据的决策框架可用于多个试验和不同的癌症部位。
Many adults with cancer are not enrolled in clinical trials because caregivers do not have the time to match the patient's clinical findings with varying eligibility criteria associated with multiple trials for which the patient might be eligible. The authors developed a point-of-use portable decision support tool (DS-TRIEL) to automate this matching process. The support tool consists of a hand-held computer with a programmable relational database. A two-level hierarchic decision framework was used for the identification of eligible subjects for two open breast cancer clinical trials. The hand-held computer also provides protocol consent forms and schemas to further help the busy oncologist. This decision support tool and the decision framework on which it is based could be used for multiple trials and different cancer sites.