Diabetes Prevention Programs
Diabetes Prevention Programs
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DOI：
10.1016/j.mcna.2010.11.006
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发表时间：
2011-03-01
影响因子：
5.9
通讯作者：
Snehalatha, C.
中科院分区：
文献类型：
--
作者：
Ramachandran, A.;Snehalatha, C.
2型糖尿病的一级预防是控制其流行的有效措施。生活方式干预已被发现是预防高危人群糖尿病的一种高效，安全和具有成本效益的方法，其益处可持续多年。在用于预防糖尿病的药物研究中，二甲双胍被发现是最安全的。使用药物的干预不太可取，因为药物的影响往往在停止使用后消失，也可能产生不良影响。主要的挑战是将现有的知识转化为国家一级的预防方案。
Primary prevention of type 2 diabetes is effective for curbing its epidemic. Lifestyle intervention has been found to be a highly effective, safe, and cost-effective method for the prevention of diabetes in high-risk persons, the benefit of which can extend for many years. Among the pharmacologic agents studied for prevention of diabetes, metformin has been found to be the safest. Interventions using drugs are less preferred because the drugs' effects tend to dissipate after their use is stopped and adverse effects may also result. The major challenge is to translate current knowledge into prevention programs at the national level.