Presbyacusis and the auditory brainstem response

Presbyacusis and the auditory brainstem response
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DOI:
10.1044/1092-4388(2002/100
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发表时间:
2002-12-01
影响因子:
2.6
通讯作者:
Boettcher, FA
Boettcher, FA
中科院分区:
医学2区
文献类型:
--
作者:
Boettcher, FA

文献摘要

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听觉相关性听力损失(ARHL或老年性聋)是由于人口统计学变化而导致的感音神经性听力损失(SNHL)的一种日益常见的形式,而听觉脑干反应(ABR)是听力学和神经学中常用的实验和临床工具。与年轻成人的ABR相比,老年听觉系统中发生的一些变化可能会显著影响ABR的解释。本综述的方法将整合从人类和动物研究的生理和组织病理学数据,以提供一个更好的理解阵列的年龄相关的变化,在ABR和确定如何ODE相关的变化,在听觉系统可能会影响如何ABR应在老年性聋解释。数据将被描述的阈值,潜伏期,和振幅,以及更复杂的听觉功能,如掩蔽和时间处理。在数据审查中,将尝试区分可能严格由于阈值升高引起的年龄相关效应与可能由于老化过程引起的效应。
Age-related hearing loss (ARHL or presbyacusis) is an increasingly common form of sensorineural hearing loss (SNHL) as a result of changing demographics, and the auditory brainstem response (ABR) is a common experimental and clinical tool in audiology and neurology. Some of the changes that occur in the aging auditory system may significantly influence the interpretation of the ABR in comparison to the ABRs of younger adults. The approach of this review will be to integrate physiological and histopathological data from human and animal studies to provide a better understanding of the array of age-related changes in the ABR and to determine how ode-related changes in the auditory system may influence how the ABR should be interpreted in presbyacusis. Data will be described in terms of thresholds, latencies, and amplitudes, as well as more complex auditory functions such as masking and temporal processing. Included in the review of data will be an attempt to differentiate between age-related effects that may strictly be due to threshold elevation from those that may be due to the aging process.